Article
The role of ATP-binding-cassette-transporter-A1 (ABCA1) gene polymorphism on coronary artery disease risk.
Translational research : the journal of laboratory and clinical medicine - 1 Apr 2010
Doosti Mahmoud, Najafi Mahdi, Reza Javad Zavar, Nikzamir Abdolrahim
Abstract excerpt
ATP-binding cassette transporter A1 (ABCA1) plays a pivotal role in intracellular cholesterol removal and exerts a protective effect against atherosclerosis. The role of genetic factors in susceptibility to coronary artery disease (CAD) is not clear. The aim of this study was to evaluate for the first time the possible association between R219K gene polymorphism and coronary artery disease in an Iranian adult...
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