Article
EMT and Back Again: Visualizing the Dynamic Phenotypes of Metastasis.
Cancer research - 15 Jan 2020
Bunz Fred
Abstract excerpt
To what extent does the acquisition of mesenchymal phenotypes by tumor epithelial cells contribute to metastasis? A definitive answer to this question has remained elusive despite much experimentation and debate. Recently, an influential study based on fluorescence-based lineage tracing technology provided evidence that very few of the cells that populate experimental metastases in fact undergo the...
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