Epithelial-to-Mesenchymal Transition Is Important to Metastasis, But Questions Remain

Abstract excerpt

How tumors spread and kill their hosts remains a mystery. To metastasize, cancer cells must break many fundamental rules of normal cellular behavior: They detach from neighboring cells, move freely on their own, enter the bloodstream and survive there, and finally exit into new tissue and colonize it. The whole area of metastasis has been “one of unfathomable complexity,” MIT cancer researcher Robert Weinberg,...

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