Article
Population-specific signatures of intra-individual mitochondrial DNA heteroplasmy and their potential evolutionary advantages.
Scientific reports - 14 Jan 2020
Tikochinski Yaron, Carreras Carlos, Tikochinski Gili, Vilaça Sibelle T
Abstract excerpt
Heteroplasmy is the existence of more than one mitochondrial DNA (mtDNA) variant within a cell. The evolutionary mechanisms of heteroplasmy are not fully understood, despite being a very common phenomenon. Here we combined heteroplasmy measurements using high throughput sequencing on green turtles (Chelonia mydas) with simulations to understand how heteroplasmy modulates population diversity across generations...
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