Article
A thirty million year-old inherited heteroplasmy.
PloS one - 13 Aug 2008
Doublet Vincent, Souty-Grosset Catherine, Bouchon Didier, Cordaux Richard, Marcadé Isabelle
Abstract excerpt
Due to essentially maternal inheritance and a bottleneck effect during early oogenesis, newly arising mitochondrial DNA (mtDNA) mutations segregate rapidly in metazoan female germlines. Consequently, heteroplasmy (i.e. the mixture of mtDNA genotypes within an organism) is generally resolved to ho...
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