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Article

Resumption of Autophagy by Ubisol-Q10 in Presenilin-1 Mutated Fibroblasts and Transgenic AD Mice: Implications for Inhibition of Senescence and Neuroprotection.

Oxidative medicine and cellular longevity - 1 Jan 2019

Vegh Caleb, Pupulin Simon, Wear Darcy, Culmone Lauren, Huggard Rachel, Ma Dennis, Pandey Siyaram

Abstract excerpt

Alzheimer's disease (AD) is the most prevalent form of dementia and is associated with loss of memory, amyloid-beta plaque buildup, and neurofibrillary tangles. These features might be a result of neuronal cell death in the cerebral cortex and hippocampal regions of the brain. AD pathologies can be attributed to a variety of biochemical consequences including mitochondrial dysfunction, increased oxidative stress,...

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Identifiers

PMID: 31934268
DOI: 10.1155/2019/7404815
PMCID: PMC6942887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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