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Article

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Genes and immunity - 1 Feb 2020

Bonomi Alice, Veglia Fabrizio, Baldassarre Damiano, Strawbridge Rona J, Golabkesh Zahra, Sennblad Bengt, Leander Karin, Smit Andries J, Giral Philippe, Humphries Steve E, Tremoli Elena, Hamsten Anders, de Faire Ulf, Gigante Bruna

Abstract excerpt

The genes regulating circulating levels of soluble gp130 (sgp130), the antagonist of the inflammatory response in atherosclerosis driven by interleukin 6, are largely unknown. Aims of the present study were to identify genetic loci associated with circulating sgp130 and to explore the potential association between variants associated with sgp130 and markers of subclinical atherosclerosis. The study is based on...

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Identifiers

PMID: 31932740
DOI: 10.1038/s41435-019-0090-z
PMCID: PMC7182533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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