Article
Omentin: a biomarker of cardiovascular risk in individuals with axial spondyloarthritis.
Scientific reports - 15 Jun 2020
Genre Fernanda, Rueda-Gotor Javier, Remuzgo-Martínez Sara, Pulito-Cueto Verónica, Corrales Alfonso, Mijares Verónica, Lera-Gómez Leticia, Portilla Virginia, Expósito Rosa, Mata Cristina, Blanco Ricardo, Llorca Javier, Hernández-Hernández Vanesa, Vicente Esther, Fernández-Carballido Cristina, Martínez-Vidal María Paz, Castro-Corredor David, Anino-Fernández Joaquín, Rodríguez-Lozano Carlos, Gualillo Oreste, Quevedo-Abeledo Juan Carlos, Castañeda Santos, Ferraz-Amaro Iván, López-Mejías Raquel, González-Gay Miguel Á
Abstract excerpt
Cardiovascular (CV) disease is the main cause of mortality in axial spondyloarthritis (axSpA). CV risk is enhanced by dysregulation of adipokines. Low omentin levels were associated with metabolic dysfunction and CV disease in conditions different from axSpA. Accordingly, we evaluated the genetic and functional implication of omentin in CV risk and subclinical atherosclerosis in a cohort of 385 axSpA patients....
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