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Article

Unique and non-redundant function of csf1r paralogues in regulation and evolution of post-embryonic development of the zebrafish.

Development (Cambridge, England) - 22 Jan 2020

Caetano-Lopes Joana, Henke Katrin, Urso Katia, Duryea Jeffrey, Charles Julia F, Warman Matthew L, Harris Matthew P

Abstract excerpt

Evolution is replete with reuse of genes in different contexts, leading to multifunctional roles of signaling factors during development. Here, we explore osteoclast regulation during skeletal development through analysis of colony-stimulating factor 1 receptor (csf1r) function in the zebrafish. A primary role of Csf1r signaling is to regulate the proliferation, differentiation and function of myelomonocytic...

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Identifiers

PMID: 31932352
DOI: 10.1242/dev.181834
PMCID: PMC6983717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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