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Article

Knockout of zebrafish colony-stimulating factor 1 receptor by CRISPR/Cas9 affects metabolism and locomotion capacity.

Biochemical and biophysical research communications - 30 Apr 2021

Meng Huiling, Shang Yue, Cheng Yajia, Wang Kexin, Yu Jing, Cao Peipei, Fan Saijun, Li Yuhao, Cui Jianlin

Abstract excerpt

Colony-stimulating factor 1 receptor (CSF1R) is a tyrosine kinase receptor and a key regulator of proliferation, differentiation, migration, and colonization in macrophage lineage cells. CSF1R was found to be involved in the pathogenesis of immune disorders, hematopoietic diseases, tissue damage, tumor growth and metastasis, and so on. Hence, understanding the role of CSF1R is important. CSF1R is highly conserved...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33725575
DOI: 10.1016/j.bbrc.2021.02.122

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