Article
Investigation of a rapidly spreading tuberculosis outbreak using whole-genome sequencing.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2020
Comin Jessica, Chaure Armando, Cebollada Alberto, Ibarz Daniel, Viñuelas Jesús, Vitoria María Asunción, Iglesias María José, Samper Sofía
Abstract excerpt
This paper describes the application of whole-genome sequencing (WGS) to investigate an outbreak of Mycobacterium tuberculosis occurring in Aragon, Spain, where strains have been submitted to genotyping since 2004. The responsible outbreak strain appeared in our region first in 2014 and it spread to 14 patients in the following three years. WGS found low variability between the isolates with none of the SNPs...
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