Article
A whole-genome sequencing study of an X-family tuberculosis outbreak focus on transmission chain along 25 years.
Tuberculosis (Edinburgh, Scotland) - 1 Jan 2021
Comín Jessica, Cebollada Alberto, Ibarz Daniel, Viñuelas Jesús, Vitoria María Asunción, Iglesias María José, Samper Sofía
Abstract excerpt
Lineage 4/X-family of Mycobacterium tuberculosis is not very notorious, except for the CDC1551 strain. One strain of this family, named Ara50, caused one of the largest tuberculosis outbreaks of the Aragon region, Spain, during the 1990s and remained until 2018. These X-strains are characterised by high transmissibility and by carrying a low copy number of IS6110 in their genomes. Epidemiological data of the 61...
Topics
- DNA, Bacterial
- Disease Outbreaks
- Disease Transmission, Infectious
- Forecasting
- Genome, Bacterial
- Genotype
- Global Health
- Humans
- Mycobacterium tuberculosis
- Tuberculosis