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Article

Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.

Journal of molecular biology - 14 Feb 2020

Chen Yi-Chen, Chen Siou-Pei, Li Jin-Ye, Chen Pei-Chun, Lee Yi-Zong, Li Kun-Mou, Zarivach Raz, Sun Yuh-Ju, Sue Shih-Che

Abstract excerpt

CC-type chemokine ligand 5 (CCL5) is involved in the pathogenesis of many inflammatory conditions. Under physiological conditions, CCL5 oligomerization and aggregation are considered to be responsible for its inflammatory properties. The structural basis of CCL5 oligomerization remains controversial because the current oligomer models contain no consensus interactions. In this study, NMR and biophysical analyses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31931012
DOI: 10.1016/j.jmb.2019.12.049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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