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The Role of Rare Coding Variants in Parkinson's Disease GWAS Loci

13 Dec 2019

Abstract excerpt

Introduction: Genome-wide association studies (GWAS) have identified multiple loci associated with PD risk. The presence of rare variants within these loci that may account for the increased susceptibility requires further investigation. Methods: Using exome sequencing, we performed a comprehensive rare variant screen of genes located within 56 novel PD loci. We first analyzed exomes from 109 subjects in the...

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PMID: 31920912
DOI: 10.3389/fneur.2019.01284

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