Article
Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities.
Brain : a journal of neurology - 1 May 2020
Bai Qian, Xue Mengzhou, Yong V Wee
Abstract excerpt
The prognosis of intracerebral haemorrhage continues to be devastating despite much research into this condition. A prominent feature of intracerebral haemorrhage is neuroinflammation, particularly the excessive representation of pro-inflammatory CNS-intrinsic microglia and monocyte-derived macrophages that infiltrate from the circulation. The pro-inflammatory microglia/macrophages produce injury-enhancing...
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