Article
MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and edema in intracerebral hemorrhage
2022-09-06
Abstract excerpt
The functional neurological outcome of patients with intracerebral hemorrhage (ICH) strongly relates to the degree of secondary brain injury (ICH-SBI) evolving within days after the initial bleeding. Different mechanisms including the incitement of inflammatory pathways, dysfunction of the blood–brain barrier (BBB), activation of resident microglia, and an influx of blood-borne immune cells, have been hypothesized...
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Identifiers and source
- Literature Corpus work
- 42b84e39-1ba9-5250-9496-b4d9b9ba0468
- DOI
- 10.1101/2022.09.06.506660
