Article
Genomic comparison of foot-and-mouth disease virus R strain and its chick-passaged attenuated strain.
Veterinary microbiology - 12 May 2011
He Dong-Sheng, Li Kang-Ning, Lin Xiao-Min, Lin Shao-Rong, Su Dan-Ping, Liao Ming
Abstract excerpt
The present study examined the genomic differences between foot-and-mouth disease virus (FMDV) R strain and its attenuated, chick-passaged (R(304)) strain. Eleven pairs of primers were used to amplify the complete genome of FMDV R and R(304) by RT-PCR. Each fragment was cloned into pMD18-T vector and sequenced. Nucleotide analyses showed that the genome encoding regions of R and R(304) strains open reading frame...
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