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APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression.

PloS one - 1 Jan 2020

Yamazaki Hiroyuki, Shirakawa Kotaro, Matsumoto Tadahiko, Kazuma Yasuhiro, Matsui Hiroyuki, Horisawa Yoshihito, Stanford Emani, Sarca Anamaria Daniela, Shirakawa Ryutaro, Shindo Keisuke, Takaori-Kondo Akifumi

Abstract excerpt

Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) DNA cytosine deaminase 3B (A3B) is a DNA editing enzyme which induces genomic DNA mutations in multiple myeloma and in various other cancers. APOBEC family proteins are highly homologous so it is especially difficult to investigate the biology of specifically A3B in cancer cells. To easily and comprehensively investigate A3B function in...

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Identifiers

PMID: 31914134
DOI: 10.1371/journal.pone.0223463
PMCID: PMC6948746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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