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Telomere Maintenance Mechanisms in Cancer: Clinical Implications

14 Oct 2014

Abstract excerpt

The presence of immortal cell populations with an up-regulated telomere maintenance mechanism (TMM) is an almost universal characteristic of cancers, whereas normal somatic cells are unable to prevent proliferation-associated telomere shortening and have a limited proliferative potential. TMMs and related aspects of telomere structure and function therefore appear to be ideal targets for the development of...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 24975603
DOI: 10.2174/1381612820666140630101047

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