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The potential utility of telomere‐related markers for cancer diagnosis

26 Feb 2011

Abstract excerpt

The role telomeres and telomerase play in the initiation and progression of human cancers has been extensively evaluated. Telomeres are nucleoprotein complexes comprising the hexanucleotide DNA repeat sequence, TTAGGG and numerous telomere-associated proteins, including the six member Shelterin complex. The main function of the telomere is to stabilize the ends of the chromosomes. However, through multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21352473
DOI: 10.1111/j.1582-4934.2011.01284.x

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