Article
CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data.
Nature communications - 3 Jan 2020
Serin Harmanci Akdes, Harmanci Arif O, Zhou Xiaobo
Abstract excerpt
RNA sequencing experiments generate large amounts of information about expression levels of genes. Although they are mainly used for quantifying expression levels, they contain much more biologically important information such as copy number variants (CNVs). Here, we present CaSpER, a signal processing approach for identification, visualization, and integrative analysis of focal and large-scale CNV events in...
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