Article
Visualization-based discovery and analysis of genomic aberrations in microarray data.
BMC bioinformatics - 13 Jun 2005
Myers Chad L, Chen Xing, Troyanskaya Olga G
Abstract excerpt
BACKGROUND: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray-based comparative genomic hybridization (array CGH) or gene expression microarrays. However, accurate identification of amplified or deleted regions requires a combination of visual and computational analysis of these microarray data....
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