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Article

Rapid response of stage IV colorectal cancer with APC/TP53/KRAS mutations to FOLFIRI and Bevacizumab combination chemotherapy: a case report of use of liquid biopsy.

BMC medical genetics - 3 Jan 2020

Hendricks Alexander, Rosenstiel Philip, Hinz Sebastian, Burmeister Greta, Röcken Christoph, Boersch Kathrin, Schafmayer Clemens, Becker Thomas, Franke Andre, Forster Michael

Abstract excerpt

BACKGROUND: Liquid biopsies of blood plasma cell free DNA can be used to monitor treatment response and potentially detect mutations that are present in resistant clones in metastatic cancer patients. CASE PRESENTATION: In our non-interventional liquid biopsy study, a male patient in his fifties diagnosed with stage IV colorectal cancer and polytope liver metastases rapidly progressed after completing...

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Identifiers

PMID: 31900123
DOI: 10.1186/s12881-019-0941-5
PMCID: PMC6942307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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