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Article

Significance of Liquid Biopsy for Monitoring and Therapy Decision of Colorectal Cancer

28 Jan 2018

Abstract excerpt

PURPOSE: Despite therapeutic improvements, all patients with nonresectable metastatic colorectal cancer (mCRC) acquire resistance to treatment probably due to the growth of mutated clones. In contrast to tissue-based studies, liquid biopsies have enabled the opportunity to reveal emerging resistance to treatment by detecting mutated clones and noninvasively monitoring clonal dynamics during therapy. METHODS: The...

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Identifiers

PMID: 29367069
DOI: 10.1016/j.tranon.2017.12.010

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