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Integrating cfDNA Liquid Biopsy and Organoid-Based Drug Screening Reveals PI3K Signaling as a Promising Therapeutic Target in Colorectal Cancer

2023-06-26

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> The current model of precision medicine relay on biomarkers, which are mainly obtained through next generation sequencing (NGS). However, this model failed to find effective drugs for most cancer patients. The current study tried to combine liquid biopsy with functional drug test through organoid models to find potential drugs for cancer patients.<bold>Methods</b...

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Literature Corpus work
0f049d9f-7cb3-5169-b52a-c848f9300326
DOI
10.21203/rs.3.rs-3041708/v1
Open publication

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Integrating cfDNA Liquid Biopsy and Organoid-Based Drug Screening Reveals PI3K Signaling as a Promising Therapeutic Target in Colorectal CancerDOI 10.21203/rs.3.rs-3041708/v1
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