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Article

A genome alignment of 120 mammals highlights ultraconserved element variability and placenta-associated enhancers.

GigaScience - 1 Jan 2020

Hecker Nikolai, Hiller Michael

Abstract excerpt

BACKGROUND: Multiple alignments of mammalian genomes have been the basis of many comparative genomic studies aiming at annotating genes, detecting regions under evolutionary constraint, and studying genome evolution. A key factor that affects the power of comparative analyses is the number of species included in a genome alignment. RESULTS: To utilize the increased number of sequenced genomes and to provide an...

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Share to Conserved Sequence
Share to Enhancer Elements, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31899510
DOI: 10.1093/gigascience/giz159
PMCID: PMC6941714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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