Article
The evolution of ultraconserved elements with different phylogenetic origins.
BMC evolutionary biology - 5 Dec 2012
Ryu Taewoo, Seridi Loqmane, Ravasi Timothy
Abstract excerpt
BACKGROUND: Ultraconserved elements of DNA have been identified in vertebrate and invertebrate genomes. These elements have been found to have diverse functions, including enhancer activities in developmental processes. The evolutionary origins and functional roles of these elements in cellular systems, however, have not yet been determined. RESULTS: Here, we identified a wide range of ultraconserved elements...
Topics
- Animals
- Base Sequence
- Binding Sites
- Conserved Sequence
- DNA
- Evolution, Molecular
- Genetic Variation
- Genome
- Humans
- Molecular Sequence Data
- Phylogeny
- Species Specificity