Article
Ultraconserved elements in the human genome.
Science (New York, N.Y.) - 28 May 2004
Bejerano Gill, Pheasant Michael, Makunin Igor, Stephen Stuart, Kent W James, Mattick John S, Haussler David
Abstract excerpt
There are 481 segments longer than 200 base pairs (bp) that are absolutely conserved (100% identity with no insertions or deletions) between orthologous regions of the human, rat, and mouse genomes. Nearly all of these segments are also conserved in the chicken and dog genomes, with an average of 95 and 99% identity, respectively. Many are also significantly conserved in fish. These ultraconserved elements of the...
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