Article
Associations of IL1RAP and IL1RL1 gene polymorphisms with obesity and inflammation mediators.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Feb 2020
Yu Gyeong Im, Song Dae Kyu, Shin Dong Hoon
Abstract excerpt
OBJECTIVES: Obesity is attributable to high free fatty acids, ER stress, oxidative stress and inflammation. The expression of IL-33, IL-1RL1 and IL-1RAP gene was observed in human visceral white fats, pre-adipocytes and adipocytes. The aim of this study was to determine whether IL1RAP and IL1RL1 gene variants were associated with obesity and inflammation mediators. METHODS: 3 SNPs of IL1RAP (rs9990107, rs3836449...
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