Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity.

doi:10.1210/jc.2010-2639

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Article

Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity.

The Journal of clinical endocrinology and metabolism - 1 Jun 2011

Jiao Hong, Arner Peter, Dickson Suzanne L, Vidal Hubert, Mejhert Niklas, Henegar Corneliu, Taube Magdalena, Hansson Caroline, Hinney Anke, Galan Pilar, Simon Chantal, Silveira Angela, Benrick Anna, Jansson John-Olov, Bouloumié Anne, Langin Dominique, Laville Martine, Debard Cyrille, Axelsson Tomas, Rydén Mikael, Kere Juha, Dahlman-Wright Karin, Hamsten Anders, Clement Karine, Dahlman Ingrid

Abstract excerpt

CONTEXT: Previous studies suggest a role for fibroblast growth factor receptor 1 (FGFR1) in the regulation of energy balance. OBJECTIVE: Our objective was to investigate whether FGFR1 is an obesity gene by genetic association and functional studies. DESIGN: The study was designed to genotype common FGFR1 single-nucleotide polymorphisms (SNP) in large cohorts, confirm significant results in additional cohorts, and...

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PMID: 21430024
DOI: 10.1210/jc.2010-2639

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FGFR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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