Article
Nucleolin promotes Ang II-induced phenotypic transformation of vascular smooth muscle cells by regulating EGF and PDGF-BB.
Journal of cellular and molecular medicine - 1 Jan 2020
Fang Li, Wang Kang-Kai, Zhang Peng-Fei, Li Tao, Xiao Zhi-Lin, Yang Mei, Yu Zai-Xin
Abstract excerpt
RNA-binding properties of nucleolin play a fundamental role in regulating cell growth and proliferation. We have previously shown that nucleolin plays an important regulatory role in the phenotypic transformation of vascular smooth muscle cells (VSMCs) induced by angiotensin II (Ang II). In the present study, we aimed to investigate the molecular mechanism of nucleolin-mediated phenotypic transformation of VSMCs...
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