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Article

miR-200a-3p inhibits the PDGF-BB-induced proliferation of VSMCs by affecting their phenotype-associated proteins.

Journal of biochemical and molecular toxicology - 1 Apr 2024

Zeng Rui-Yuan, Jin Hong-Yi, Peng Yong-Bo, Wang Wen-Jun, Cao Yuan-Ping, Peng Han-Zhi, Qiu Zhi-Cong, Lai Song-Qing, Wan Li

Abstract excerpt

Accumulating evidence shows that the abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) can significantly affect the long-term prognosis of coronary artery bypass grafting. This study aimed to explore the factors affecting the proliferation, migration, and phenotypic transformation of VSMCs. First, we stimulated VSMCs with different platelet-derived growth factor-BB (PDGF-BB)...

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Becaplermin
Cell Movement
Cell Proliferation
Cells, Cultured
MicroRNAs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muscle, Smooth, Vascular

Myocytes, Smooth Muscle

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PMID: 38488158
DOI: 10.1002/jbt.23675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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