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Article

Decreased amplitude and reliability of odor-evoked responses in two mouse models of autism.

Journal of neurophysiology - 1 Apr 2020

Geramita Matthew A, Wen Jing A, Rannals Matthew D, Urban Nathan N

Abstract excerpt

Sensory processing deficits are increasingly recognized as core symptoms of autism spectrum disorders (ASDs). However the molecular and circuit mechanisms that lead to sensory deficits are unknown. We show that two molecularly disparate mouse models of autism display similar deficits in sensory-evoked responses in the mouse olfactory system. We find that both Cntnap2- and Shank3-deficient mice of both sexes...

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Identifiers

PMID: 31891524
DOI: 10.1152/jn.00277.2019
PMCID: PMC7191528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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