Article
Shared and divergent alteration of whole-brain connectivity and sensory deficits in multiple autism mouse models.
Molecular psychiatry - 1 Apr 2026
Hsu Tsan-Ting, Chen Chih-Ping, Lin Ming-Hui, Hung Tzu-En, Haung Tzyy-Nan, Wang Chien-Yao, Hsueh Yi-Ping
Abstract excerpt
Autism spectrum disorder (ASD) is a heterogeneous developmental disconnection syndrome. Identifying circuit deficits is crucial for understanding ASD etiology, yet the involvement of multiple brain regions and genetic variations complicates this analysis. Here, using an AI-powered mapping platform, BM-auto (Brain Mapping with Auto-ROI correction), to analyze a Thy1-YFP reporter, we show that different...
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