Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estrogen activates Alzheimer's disease genes

1 Jan 2019

Abstract excerpt

Abstract Introduction Women are at increased risk for Alzheimer's disease (AD), but the reason why remains unknown. One hypothesis is that low estrogen levels at menopause increases vulnerability to AD, but this remains unproven. Methods We compared neuronal genes upregulated by estrogen in ovariectomized female rhesus macaques with a database of >17,000 diverse gene sets and applied a rare variant burden test to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cancer-related cognitive impairment studies
Share to Menopause: Health Impacts and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31890855
DOI: 10.1016/j.trci.2019.09.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estrogen activates Alzheimer's disease genesPMID 31890855Read ↗

Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer’s diseaseSemantic proximity Read ↗

Estrogen associated gene polymorphisms and their interactions in the progress of Alzheimer's disease.Semantic proximity Read ↗

Identification of Progesterone-Associated Gene Signatures in Men with Alzheimer’s Disease Using Public Transcriptomic DataSemantic proximity Read ↗

Women’s brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer’s diseaseSemantic proximity Read ↗

Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease.Semantic proximity Read ↗

Role of estrogen in women's Alzheimer's disease risk as modified by APOE.Semantic proximity Read ↗

Shared Risk Genes and Casual Relationships across Sex Hormone Related Traits and Alzheimer’s DiseaseSemantic proximity Read ↗

Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sexual dimorphism in late-onset Alzheimer’s diseaseSemantic proximity Read ↗

Sex-specific Associations of Gene Expression with Alzheimer’s Disease Neuropathology and Ante-mortem Cognitive PerformanceSemantic proximity Read ↗

Sex-specific Associations of Gene Expression with Alzheimer’s Disease Neuropathology and Ante-mortem Cognitive PerformanceSemantic proximity Read ↗

Association of the aromatase gene with Alzheimer's disease in women.Semantic proximity Read ↗

Are the estrogen receptors involved in Alzheimer's disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.