Article
HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist.
Oxidative medicine and cellular longevity - 1 Jan 2019
Bayurova Ekaterina, Jansons Juris, Skrastina Dace, Smirnova Olga, Mezale Dzeina, Kostyusheva Anastasia, Kostyushev Dmitry, Petkov Stefan, Podschwadt Philip, Valuev-Elliston Vladimir, Sasinovich Sviataslau, Korolev Sergey, Warholm Per, Latanova Anastasia, Starodubova Elizaveta, Tukhvatulin Amir, Latyshev Oleg, Selimov Renat, Metalnikov Pavel, Komarov Alexander, Ivanova Olga, Gorodnicheva Tatiana, Kochetkov Sergey, Gottikh Marina, Strumfa Ilze, Ivanov Alexander, Gordeychuk Ilya, Isaguliants Maria
Abstract excerpt
HIV-induced immune suppression results in the high prevalence of HIV/AIDS-associated malignancies including Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer. HIV-infected people are also at an increased risk of "non-AIDS-defining" malignancies not directly linked to immune suppression but associated with viral infections. Their incidence is increasing despite successful antiretroviral therapy. The...
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