Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?

1 May 2008

Abstract excerpt

The acquired immunodeficiency syndrome (AIDS) is accompanied by a significant increase in the incidence of neoplasms. Several causative agents have been proposed for this phenomenon. These include immunodeficiency and oncogenic DNA viruses and the HIV-1 protein Tat. Cancer in general is closely linked to genomic instability and DNA repair mechanisms. The latter maintains genomic stability and serves as a cellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to Polyomavirus and related diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18577246
DOI: 10.1186/1756-9966-27-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?PMID 18577246Read ↗

Human Retroviruses: Their Role in CancerSemantic proximity Read ↗

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS productionSemantic proximity Read ↗

HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV TherapiesSemantic proximity Read ↗

The Complex Interactions Between HIV-1 and Human Host Cell Genome: From Molecular Mechanisms to Clinical PracticeSemantic proximity Read ↗

Reciprocal modulations between p53 and Tat of human immunodeficiency virus type 1.Semantic proximity Read ↗

HIV-1 Transactivator of Transcription (Tat) Co-operates With AP-1 Factors to Enhance c-MYC TranscriptionSemantic proximity Read ↗

Tits and bits of HIV Tat protein.Semantic proximity Read ↗

Regulation of cellular gene expression and function by the human immunodeficiency virus type 1 tat proteinSemantic proximity Read ↗

The HIV-1 tat protein enhances E2-dependent human papillomavirus 16 transcriptionSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Tat Accelerates Kaposi Sarcoma-Associated Herpesvirus Kaposin A-Mediated Tumorigenesis of Transformed Fibroblasts In Vitro as well as in Nude and Immunocompetent MiceSemantic proximity Read ↗

HIV-1 Tat induces DNMT over-expression through microRNA dysregulation in HIV-related non Hodgkin lymphomasSemantic proximity Read ↗

Tat is a multifunctional viral protein that modulates cellular gene expression and functionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.