Article
Genomic and Expression Analyses Define MUC17 and PCNX1 as Predictors of Chemotherapy Response in Breast Cancer.
Molecular cancer therapeutics - 1 Mar 2020
Al Amri Waleed S, Allinson Lisa M, Baxter Diana E, Bell Sandra M, Hanby Andrew M, Jones Stacey J, Shaaban Abeer M, Stead Lucy F, Verghese Eldo T, Hughes Thomas A
Abstract excerpt
Poor-prognosis breast cancers are treated with cytotoxic chemotherapy, but often without any guidance from therapy predictive markers because universally accepted markers are not currently available. Treatment failure, in the form of recurrences, is relatively common. We aimed to identify chemotherapy predictive markers and resistance pathways in breast cancer. Our hypothesis was that tumor cells remaining after...
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