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Article

CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer.

BMC cancer - 21 Jan 2019

Zhao Zi-Ming, Yost Susan E, Hutchinson Katherine E, Li Sierra Min, Yuan Yate-Ching, Noorbakhsh Javad, Liu Zheng, Warden Charles, Johnson Radia M, Wu Xiwei, Chuang Jeffrey H, Yuan Yuan

Abstract excerpt

BACKGROUND: Triple negative breast cancer (TNBC) is aggressive with limited treatment options upon recurrence. Molecular discordance between primary and metastatic TNBC has been observed, but the degree of biological heterogeneity has not been fully explored. Furthermore, genomic evolution through treatment is poorly understood. In this study, we aim to characterize the genomic changes between paired primary and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30665374
DOI: 10.1186/s12885-019-5290-4
PMCID: PMC6341717

Genes

CCNE1
TPX2
CEP76
ELF3
FANCL
GSK3B
JAK2
SYK

Provenance

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