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Article

Acquired Multidrug Antifungal Resistance in Candida lusitaniae during Therapy.

Antimicrobial agents and chemotherapy - 1 Dec 2015

Asner Sandra A, Giulieri Stefano, Diezi Manuel, Marchetti Oscar, Sanglard Dominique

Abstract excerpt

Candida lusitaniae is usually susceptible to echinocandins. Beta-1,3-glucan synthase encoded by FKS genes is the target of echinocandins. A few missense mutations in the C. lusitaniae FKS1 hot spot 1 (HS1) have been reported. We report here the rapid emergence of antifungal resistance in C. lusitaniae isolated during therapy with amphotericin B (AMB), caspofungin (CAS), and azoles for treatment of persistent...

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Identifiers

PMID: 26438490
DOI: 10.1128/AAC.02204-15
PMCID: PMC4649199

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Source receipt: pubmed, retrieved 7 Sept 2026.

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