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Haplotype analysis on association between variants of interleukin 6 (IL-6) and late-onset Alzheimer's disease in a Chinese Han population.

Experimental gerontology - 1 Mar 2020

Zhao Jing, Liu Ping, Hua Linlin, Yang Xiaopeng, Zeng Zhilei, Li Xiaodong, Wang Shanshan, Liu Yajun, Liu Yanqiu, Wang Yunliang

Abstract excerpt

OBJECTIVE: The aim of this study was to evaluate the influence of single nucleotide polymorphisms (SNPs) in interleukin-6 (IL-6) gene and the haplotype on late-onset Alzheimer's disease (LOAD). METHODS: A total of 896 participants were enrolled, including 446 LOAD patients and 450 controls. Total genomic DNA was extracted from the blood of participants and genotyping was then performed. Hardy-Weinberg equilibrium...

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PMID: 31874191
DOI: 10.1016/j.exger.2019.110813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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