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Article

Towards a complete resolution of the genetic architecture of disease.

Trends in genetics : TIG - 1 Oct 2010

Singleton Andrew B, Hardy John, Traynor Bryan J, Houlden Henry

Abstract excerpt

After years of linear gains in the genetic dissection of human disease we are now in a period of exponential discovery. This is particularly apparent for complex disease. Genome-wide association studies (GWAS) have provided myriad associations between common variability and disease, and have shown that common genetic variability is unlikely to explain the entire genetic predisposition to disease. Here we detail...

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Identifiers

PMID: 20813421
DOI: 10.1016/j.tig.2010.07.004
PMCID: PMC2943029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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