Article
Genetic association of E26 transformation specific sequence 1 polymorphisms with the susceptibility of primary biliary cholangitis in China.
Scientific reports - 23 Dec 2019
Xu Huan, Niu Qian, Su Zhenzhen, Wang Fang, Zhang Junlong, Yang Bin, Huang Zhuochun
Abstract excerpt
Primary biliary cholangitis (PBC) is a chronic and cholestatic liver disease characterized by an autoimmune-mediated destruction of intrahepatic bile ducts. E26 transformation specific sequence 1 (ETS-1) is a transcription factor regulating the expression of various immune-related genes. The aim of our study was to identify the associations between the gene polymorphisms of ETS-1 with the susceptibility and...
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