Article
Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma.
Thorax - 1 Sept 2015
Pilecki Bartosz, Schlosser Anders, Wulf-Johansson Helle, Trian Thomas, Moeller Jesper B, Marcussen Niels, Aguilar-Pimentel Juan A, de Angelis Martin Hrabe, Vestbo Jorgen, Berger Patrick, Holmskov Uffe, Sorensen Grith L
Abstract excerpt
BACKGROUND: Recently, several proteins of the extracellular matrix have been characterised as active contributors to allergic airway disease. Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein abundant in the lung, whose biological functions remain poorly understood. In the current study we investigated the role of MFAP4 in experimental allergic asthma. METHODS: MFAP4-deficient mice...
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