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Article

CYP17 polymorphism (rs743572) is associated with increased risk of gallbladder cancer in tobacco users.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014

Rai Rajani, Sharma Kiran L, Misra Sanjeev, Kumar Ashok, Mittal Balraj

Abstract excerpt

Gallbladder cancer (GBC) involves interplay of sex steroids, including estrogen and progesterone. Since CYP17 is a key enzyme involved in estrogen and testosterone hormone biosynthesis as well as in xenobiotic metabolism, it may be a potential candidate gene in the carcinogenesis of the gallbladder. Hence, the present study aimed to investigate the association of CYP17 (rs2486758, and rs743572) polymorphisms with...

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Identifiers

PMID: 24687554
DOI: 10.1007/s13277-014-1876-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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