Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cells

23 Dec 2019

Abstract excerpt

Glioblastoma multiforme (GBM) is the most malignant primary brain tumour in adults. Since glioma stem cells (GSCs) are associated with therapeutic resistance as well as the initiation and recurrence in GBM, therapies targeting GSCs are considered to be effective for long‐term survival in GBM. Several reports suggested that oxidative phosphorylation (OXPHOS) of cancer stem cells is important for their survival;...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glioma Diagnosis and Treatment
Share to Microtubule and mitosis dynamics
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31868973
DOI: 10.1111/febs.15187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cellsPMID 31868973Read ↗

Why All the Fuss about Oxidative Phosphorylation (OXPHOS)?Semantic proximity Read ↗

Redox-Regulated Pathways in Glioblastoma Stem-like Cells: Mechanistic Insights and Therapeutic ImplicationsSemantic proximity Read ↗

OMA1 maintains the stemness of glioma stem cells by inducing mitochondrial fission/fusion imbalanceSemantic proximity Read ↗

The interplay of mitochondrial dysfunction and altered metabolic pathways in glioblastomaSemantic proximity Read ↗

Effective Elimination of Cancer Stem Cells By a Novel Drug Combination StrategySemantic proximity Read ↗

Impact of celastrol on mitochondrial dynamics and proliferation in glioblastomaSemantic proximity Read ↗

Metabolic profiling of glioblastoma stem cells reveals pyruvate carboxylase as a critical survival factor and potential therapeutic targetSemantic proximity Read ↗

Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profileSemantic proximity Read ↗

Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastomaSemantic proximity Read ↗

DMC-BH derivative DMC-GF inhibits the growth of glioma stem cells by targeting the TRIM33/SLC25A1/mitochondrial oxidative phosphorylation pathwaySemantic proximity Read ↗

Oxidative Stress and Redox Imbalance: Common Mechanisms in Cancer Stem Cells and Neurodegenerative DiseasesSemantic proximity Read ↗

Cancer Stem Cell Metabolism and Potential Therapeutic TargetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.