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Cancer Stem Cell Metabolism and Potential Therapeutic Targets

5 Jun 2018

Abstract excerpt

Malignant tumors contain heterogeneous populations of cells in various states of proliferation and differentiation. The presence of cancer stem or initiating cells is a well-established concept wherein quiescent and poorly differentiated cells within a tumor mass contribute to drug resistance, and under permissive conditions, are responsible for tumor recurrence and metastasis. A number of studies have identified...

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Identifiers

PMID: 29922594
DOI: 10.3389/fonc.2018.00203

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