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Impact of celastrol on mitochondrial dynamics and proliferation in glioblastoma

6 Mar 2025

Abstract excerpt

BACKGROUND: Targeting mitochondrial dynamics offers promising strategies for treating glioblastoma multiforme. Celastrol has demonstrated therapeutic effects on various cancers, but its impact on mitochondrial dynamics in glioblastoma multiforme remains largely unknown. We studied the effects of Celastrol on mitochondrial dynamics, redox homeostasis, and the proliferation. METHODS: Mito-Tracker Green staining was...

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PMID: 40050778
DOI: 10.1186/s12885-025-13733-9

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