Article
Vitamin D receptor ApaI polymorphism associated with progression of liver disease in Vietnamese patients chronically infected with hepatitis B virus.
BMC medical genetics - 21 Dec 2019
Hoan Nghiem Xuan, Khuyen Nguyen, Giang Dao Phuong, Binh Mai Thanh, Toan Nguyen Linh, Anh Do Tuan, Trung Ngo Tat, Bang Mai Hong, Meyer Christian G, Velavan Thirumalaisamy P, Song Le Huu
Abstract excerpt
BACKGROUND: Vitamin D derivatives and their receptor (VDR) are potent modulators of immune responses in various diseases including malignancies as well as in metabolic and infectious disorders. The impact of vitamin D receptor polymorphisms on clinical outcomes of hepatitis B virus (HBV) infection is not well understood. This study aims to investigate the potential role of VDR polymorphisms (TaqI, FokI, ApaI, and...
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