Article
Single-nucleotide polymorphism at CYP27B1-1260, but not VDR Taq I, is possibly associated with persistent hepatitis B virus infection.
Genetic testing and molecular biomarkers - 1 Sept 2012
Zhu Qianqian, Li Na, Han Qunying, Li Zhu, Zhang Guoyu, Li Fang, Zhang Pingping, Chen Jinghong, Lv Yi, Liu Zhengwen
Abstract excerpt
BACKGROUND: Vitamin D, beyond its role in calcium and bone metabolism, exhibits immunomodulatory effects on innate and adaptive immune pathways and is suggestively related to liver diseases. OBJECTIVE: This study investigated the association of single-nucleotide polymorphisms in genes involved in vitamin D functions with hepatitis B virus (HBV) infection. METHODS: Five hundred Chinese Han subjects, including 274...
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